![]() Whitehead Institute Member David Bartel’s lab discovered in 2014 ways in which cells regulate protein production differently during this early developmental period, using processes that modulate how efficiently existing mRNAs are translated into proteins, rather than destroying mRNAs to decrease the protein level. However, in the earliest stages of development, before the embryo can make enough of its own mRNAs, they are a limited resource and the embryo cannot afford to destroy them. Usually, mRNAs are short lived, constantly being created and degraded to help regulate how much protein is made from a gene at any given time. Early in development, eggs and embryos use mRNA supplied by the mother until the embryo starts making enough mRNA from its own genes. In order for the instructions in our genes to be carried out, first their DNA sequences are copied into mRNA, and then that mRNA is used as a template to create proteins that do the work of the cell. Messenger RNAs (mRNAs) are our cells’ intermediaries as genes become proteins. Remembering Stephen Goldman (1962 – 2022).Gould MIT Summer Research Program in Biology (BSG-MSRP-Bio) Workshops for MIT Biology Postdocs Entering the Academic Job Market.Interdisciplinary and Joint Degree Programs. ![]() Biology Undergraduate Student Association.Biochemistry, Biophysics, and Structural Biology. ![]()
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